Detalhe da pesquisa
1.
A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K(+) Channels.
Cell
; 164(5): 937-49, 2016 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26919430
2.
Missense mutations in PIEZO1, which encodes the Piezo1 mechanosensor protein, define Er red blood cell antigens.
Blood
; 141(2): 135-146, 2023 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36122374
3.
Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes.
Basic Res Cardiol
; 118(1): 14, 2023 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37020075
4.
The suitability of high throughput automated patch clamp for physiological applications.
J Physiol
; 600(2): 277-297, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34555195
5.
A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm.
Toxicol Appl Pharmacol
; 394: 114961, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32209365
6.
pH-sensitive K(+) channel TREK-1 is a novel target in pancreatic cancer.
Biochim Biophys Acta
; 1862(10): 1994-2003, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27443495
7.
The pore structure and gating mechanism of K2P channels.
EMBO J
; 30(17): 3607-19, 2011 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-21822218
8.
Corrigendum to "A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm" [Toxicology and Applied Pharmacology volume 394C (2020) 114961].
Toxicol Appl Pharmacol
; 395: 114983, 2020 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32247767
9.
Side pockets provide the basis for a new mechanism of Kv channel-specific inhibition.
Nat Chem Biol
; 9(8): 507-13, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23728494
10.
RNA editing modulates the binding of drugs and highly unsaturated fatty acids to the open pore of Kv potassium channels.
EMBO J
; 29(13): 2101-13, 2010 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20461057
11.
A novel gain-of-function mutation of Piezo1 is functionally affirmed in red blood cells by high-throughput patch clamp.
Haematologica
; 104(5): e179-e183, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30237269
12.
Voltage-dependent gating in a "voltage sensor-less" ion channel.
PLoS Biol
; 8(2): e1000315, 2010 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20208975
13.
KCNJ10 gene mutations causing EAST syndrome (epilepsy, ataxia, sensorineural deafness, and tubulopathy) disrupt channel function.
Proc Natl Acad Sci U S A
; 107(32): 14490-5, 2010 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20651251
14.
A high-throughput electrophysiology assay to study the response of PIEZO1 to mechanical stimulation.
J Gen Physiol
; 155(12)2023 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37801066
15.
Atrial fibrillation-associated electrical remodelling in human induced pluripotent stem cell-derived atrial cardiomyocytes: a novel pathway for antiarrhythmic therapy development.
Cardiovasc Res
; 119(16): 2623-2637, 2023 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37677054
16.
A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes.
Commun Biol
; 5(1): 969, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36109584
17.
There is no F in APC: Using physiological fluoride-free solutions for high throughput automated patch clamp experiments.
Front Mol Neurosci
; 15: 982316, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36072300
18.
H bonding at the helix-bundle crossing controls gating in Kir potassium channels.
Neuron
; 55(4): 602-14, 2007 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-17698013
19.
5-Hydroxydecanoate and coenzyme A are inhibitors of native sarcolemmal KATP channels in inside-out patches.
Biochim Biophys Acta
; 1800(3): 385-91, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19931596
20.
Reliable identification of cardiac conduction abnormalities in drug discovery using automated patch clamp II: Best practices for Nav1.5 peak current in a high throughput screening environment.
J Pharmacol Toxicol Methods
; 112: 107125, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34500078